Dry Skin

Reduced skin moisture and impaired barrier function. A common concern with a strong evidence base for barrier-focused ingredients.

Understanding evidence levels
In VitroCell or tissue culture experiments — no human or animal data.
Ex VivoSkin model or tissue experiments — not in living humans.
Animal StudyResults in animals only — may or may not translate to humans.
Small Human StudySmall or uncontrolled human study — preliminary results.
Controlled TrialControlled human study (often randomized) — stronger evidence.
Systematic ReviewSummary and analysis of existing published studies.
Meta-AnalysisStatistical pooling of results from multiple studies.
GuidelineProfessional guidance or consensus statement from a dermatology society.

Research findings(115)

Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Controlled TrialControlled human study, often randomized. Stronger evidence.Published: May 15, 2026

Oral Rice Bran Oil May Help Improve Skin Moisture Levels

A small study suggests that taking rice bran oil orally may improve skin moisture levels. Researchers found that participants who took the oil had higher skin moisture levels after 12 weeks compared to those who took a placebo. The study also found that the oil may help reduce redness and improve skin satisfaction.

Why it matters: This study may help us understand how oral supplements can impact skin health and potentially lead to new treatments for dry skin.

The study had a small sample size of 70 participants and was conducted over a short period of 12 weeks. The study only looked at the effects of the oil on skin moisture levels and did not examine other potential benefits or side effects.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.Published: May 13, 2026

Chlorophytum borivilianum may help alleviate symptoms of atopic dermatitis

Researchers studied the effects of Chlorophytum borivilianum root extract on a skin condition called atopic dermatitis in mice. They found that the extract improved symptoms and reduced inflammation. The study suggests that Chlorophytum borivilianum may have anti-inflammatory and antioxidant properties.

Why it matters: This study may contribute to the understanding of natural treatments for atopic dermatitis, a chronic skin condition.

This study was conducted in mice and may not translate to human skin. Further research is needed to confirm the findings.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.Published: May 12, 2026

Cold Plasma May Help Improve Skin Barrier in Kidney Disease

Researchers studied how cold atmospheric plasma affects skin barrier function in people with chronic kidney disease. They found that it may help improve skin barrier function by promoting cell growth and differentiation. This could alleviate skin complications associated with kidney disease.

Why it matters: This study may contribute to a better understanding of how to manage skin complications in people with chronic kidney disease.

This study used adenine-induced CKD mice and HaCaT cells, and its findings may not directly apply to humans. Further research is needed to confirm these results in human subjects.

PubMed
Small Human StudySmall or uncontrolled human study. Results are preliminary.Published: May 1, 2026

DYNAMiQ Technology May Help Improve Skin Barrier Function

Researchers studied a technology called DYNAMiQ to see if it could improve the skin's ability to retain moisture. A small group of women received one treatment and their skin's water loss was measured before and after. The results showed that their skin's ability to retain moisture improved significantly over time.

Why it matters: Understanding how to improve skin barrier function may help people with skin issues such as dryness and sensitivity.

This study had a small sample size of 24 women and only one treatment was given, so it's unclear if the results would be the same with repeated treatments or in people with different skin types.

PubMed
Small Human StudySmall or uncontrolled human study. Results are preliminary.Published: April 30, 2026

Bed baths with weak wiping pressure may not harm skin barrier function in older patients with heart disease

A small study investigated the effects of bed baths with weak wiping pressure on the skin barrier function of older patients with heart disease. Researchers found that a single bed bath did not cause sustained impairment of skin barrier function. However, they did observe some temporary changes in skin hydration.

Why it matters: This study may help healthcare professionals understand how to care for the skin of older patients with heart disease without causing harm.

This study had a small sample size of 33 participants and only investigated the effects of a single bed bath.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.Published: April 14, 2026

Liquiritin Carbomer Gel May Help Alleviate Atopic Dermatitis Symptoms

Researchers studied a gel containing liquiritin, a compound found in licorice, to see if it could help with atopic dermatitis, a chronic skin condition. They found that the gel may help reduce symptoms by repairing the skin barrier and reducing inflammation. However, more research is needed to confirm these findings.

Why it matters: This study may contribute to the development of safer, more effective treatments for atopic dermatitis.

This study was conducted in mice and may not translate to human skin. The gel's effects were observed in a controlled lab setting, and its long-term safety and efficacy in humans are unknown.

PubMed
Small Human StudySmall or uncontrolled human study. Results are preliminary.CeramidesPublished: April 13, 2026

Ceramide Levels in Dry Skin Studied Using Advanced Lab Technique

Researchers used a new lab method to study ceramide levels in people with dry skin. They found differences in ceramide levels between people with sensitive dry skin, non-sensitive dry skin, and normal skin. The study suggests that these differences might be linked to skin barrier problems and inflammation.

Why it matters: Understanding ceramide levels in dry skin may help researchers develop new treatments for sensitive skin conditions.

This study was conducted on a small group of 93 adult female volunteers, and the results may not be representative of all people with dry skin. The study was conducted in a lab setting using tape stripping to collect skin samples.

PubMed
In VitroCell or tissue culture experiments. No human or animal data.Lactic AcidPublished: April 6, 2026

New Wound Dressing May Help Promote Healing and Prevent Infection

Researchers created a new type of wound dressing that uses light to help wounds heal faster and prevent infection. This dressing is made from tiny particles of cellulose and a metal compound called MoS. In lab experiments, it showed promise in absorbing moisture, blocking UV light, and killing bacteria. When exposed to near-infrared light, it became even more effective at killing bacteria.

Why it matters: This research may help improve wound care and prevent infections, which can be a major concern for people with open wounds.

This study was conducted in a lab and has not been tested in humans. Further research is needed to confirm its effectiveness and safety in real-world settings.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.PeptidesPublished: March 27, 2026

Sea Cucumber Collagen Peptides May Help Improve Skin Aging

Researchers studied the effects of sea cucumber collagen peptides on skin aging in mice. They found that these peptides may help improve skin barrier function and reduce signs of aging. However, more research is needed to confirm these findings.

Why it matters: This study may provide insights into new ways to prevent or mitigate skin aging, which is a complex biological process.

This study was conducted in mice and its findings may not directly apply to humans. Further research is needed to confirm the efficacy of sea cucumber collagen peptides in humans.

PubMed
Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Controlled TrialControlled human study, often randomized. Stronger evidence.Hyaluronic AcidPublished: March 1, 2026

Sulfated Exopolysaccharide Extract May Help Improve Skin Hydration and Radiance

Researchers studied an extract from a red microalga that's rich in a sulfated exopolysaccharide and polydeoxyribonucleotides. In lab experiments and a small human trial, the extract showed potential to improve skin hydration, elasticity, and volume, similar to hyaluronic acid. However, more research is needed to confirm these findings.

Why it matters: This study may help our understanding of natural alternatives for improving skin appearance and hydration.

A small double-blind clinical trial was conducted with a limited number of participants, and the study duration is not specified.

PubMed
Small Human StudySmall or uncontrolled human study. Results are preliminary.Published: February 28, 2026

Platelet-Rich Fibrin and Epidermal Growth Factor Creams May Improve Skin Hydration and Elasticity

Researchers studied the effects of creams containing platelet-rich fibrin or epidermal growth factor on skin hydration and elasticity in a small group of healthy volunteers. The study found that these creams may improve skin barrier function and increase skin hydration and elasticity. However, more research is needed to confirm these findings.

Why it matters: Understanding the effects of these creams on skin health may help inform the development of new skincare products.

This study involved a small group of 20 healthy volunteers and had a short duration of four weeks. The results may not be generalizable to other populations or skin types.

PubMed
Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Systematic ReviewSummary and analysis of existing published studies.Published: February 1, 2026

Candidiasis of Skin and Nails Studied in US Health Insurance Claims Data

Researchers analyzed data from US health insurance claims to understand the prevalence and treatment of skin and nail candidiasis. They found that this condition is relatively common, but more data is needed to fully understand it. The study looked at how often people were treated for skin and nail candidiasis and what treatments they received.

Why it matters: Understanding the prevalence and treatment patterns of skin and nail candidiasis may help dermatologists and healthcare providers better diagnose and manage this condition.

This study used health insurance claims data, which may not capture all cases of skin and nail candidiasis. The study's findings are based on a retrospective analysis of existing data, which may have limitations in terms of accuracy and completeness.

PubMed