Ingredients / Hyaluronic Acid

Hyaluronic Acid

A glycosaminoglycan humectant. Widely used for hydration. Evidence is strong for surface hydration effects.

Understanding evidence levels
In VitroCell or tissue culture experiments — no human or animal data.
Ex VivoSkin model or tissue experiments — not in living humans.
Animal StudyResults in animals only — may or may not translate to humans.
Small Human StudySmall or uncontrolled human study — preliminary results.
Controlled TrialControlled human study (often randomized) — stronger evidence.
Systematic ReviewSummary and analysis of existing published studies.
Meta-AnalysisStatistical pooling of results from multiple studies.
GuidelineProfessional guidance or consensus statement from a dermatology society.

Research findings(178)

Animal StudyResults in animals only. May or may not translate to humans.Skin Barrier DamagePublished: June 4, 2026

Citrus Pomace Extract May Help Protect Skin from Damage

Researchers studied a new way to extract beneficial compounds from citrus pomace, a byproduct of citrus juice production. They found that the resulting extract, when tested in lab experiments and on mice, showed potential skin-protective effects. The extract may help reduce inflammation and improve skin barrier function.

Why it matters: This research could lead to the development of new skincare products or ingredients that help protect skin from environmental stressors.

This study was conducted in lab experiments and on mice, and its findings may not directly translate to human skin. Further research is needed to confirm these results.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.Published: June 1, 2026

New Hydrogel May Help Treat Infected Diabetic Wounds

Researchers developed a special hydrogel that may help treat infected diabetic wounds by killing bacteria and reducing inflammation. In lab experiments, the hydrogel was able to eliminate nearly all bacteria and promote healing in infected wounds. However, more studies are needed to confirm these findings.

Why it matters: This research may help improve our understanding of how to treat complex skin infections and promote wound healing.

This study was conducted in lab experiments using animal models and may not directly translate to human skin. Further research is needed to confirm these findings and determine the safety and efficacy of this hydrogel in humans.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.Published: May 29, 2026

Sprayable Nanoplatform May Help Diabetic Wounds Heal Faster

Researchers developed a sprayable nanoplatform that combines a hyaluronic acid hydrogel with a near-infrared light-activated system. This system may help clear oxidative stress, promote blood vessel growth, and fight infection in diabetic wounds. In lab experiments and animal studies, the nanoplatform showed promise in accelerating wound healing.

Why it matters: This research may contribute to the development of new treatments for diabetic wounds, which can be challenging to heal.

This study was conducted in lab experiments and animal models, and its findings may not directly apply to human skin. Further research is needed to confirm the effectiveness and safety of this nanoplatform in humans.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.Redness / Facial RednessPublished: May 25, 2026

Tetrandrine Nanocrystals May Help Treat Psoriasis

Researchers studied a new way to deliver a natural compound called tetrandrine to the skin to see if it could help treat psoriasis. They created tiny particles of tetrandrine and mixed them with a gel. In lab experiments and animal studies, the tetrandrine particles seemed to penetrate the skin better and reduce inflammation. The treated skin looked and acted healthier.

Why it matters: This study may help us understand how to deliver natural compounds to the skin more effectively for treating skin conditions like psoriasis.

This study was conducted in a lab and on animals, and its findings may not translate directly to humans. Further research is needed to confirm these results.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.AcnePublished: May 21, 2026

New Skin Patch May Help Deliver Antibacterial Treatment for Acne

Researchers developed a skin patch with tiny needles that can deliver a treatment to help fight acne-causing bacteria. In lab experiments, this patch was able to slowly release the treatment over several days and reduce inflammation in a mouse model of acne. While promising, more studies are needed to confirm its effectiveness in humans.

Why it matters: This research may help improve our understanding of how to effectively treat acne, a common skin condition.

This study was conducted in a mouse model of acne and in lab experiments, so its results may not translate directly to humans. Further research is needed to confirm its effectiveness and safety in people.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.Published: May 15, 2026

Researchers Develop New Wound Dressing for Infected Skin

A new type of wound dressing was studied for its potential to treat infected skin wounds. The dressing contains a combination of materials that may help kill bacteria and promote healing. In lab experiments, it showed promise in treating wounds infected with antibiotic-resistant bacteria.

Why it matters: This research may help improve treatments for stubborn skin infections.

This study was conducted in a lab and on animals, and its results may not translate to human skin. Further research is needed to confirm its effectiveness in people.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.Skin Barrier DamagePublished: May 14, 2026

Chum Salmon By-Products May Help Improve Skin Hydration

Researchers studied the effects of chum salmon by-product enzyme hydrolysates on skin health in mice. They found that the supplement may help improve skin hydration and reduce water loss. The study suggests that this could be due to the supplement's ability to regulate water transport and promote collagen production.

Why it matters: This research may help us better understand how certain dietary supplements can support skin health and hydration.

This study was conducted in mice and its findings may not directly apply to humans. Further research is needed to confirm these results.

PubMed
Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Controlled TrialControlled human study, often randomized. Stronger evidence.AcnePublished: May 1, 2026

Non-Cross-Linked Hyaluronic Acid Mesotherapy May Help Post-Acne Erythema

A small study looked at whether non-cross-linked hyaluronic acid mesotherapy can help reduce post-acne erythema. Researchers found that patients who received the treatment showed improvements in skin appearance and quality of life. However, more research is needed to confirm these findings.

Why it matters: Understanding how to effectively treat post-acne erythema can help people manage the appearance and symptoms of acne.

This study had a small sample size of 25 patients and was conducted at a single center. The duration of the study was 12 weeks, and the long-term effects of the treatment are not known.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.AcnePublished: April 29, 2026

Ferrous lactate-loaded hydrogels may help treat acne

Researchers studied a new type of hydrogel that contains ferrous lactate, which may help kill bacteria that cause acne. In lab experiments and animal studies, the hydrogel showed promise in reducing inflammation and promoting lesion resolution. However, more research is needed to confirm these findings.

Why it matters: This study may lead to new, non-antibiotic treatments for acne and other skin conditions caused by anaerobic bacteria.

This study was conducted in a rat model and in lab experiments, so its results may not directly apply to humans. Further research is needed to confirm the safety and efficacy of ferrous lactate-loaded hydrogels in humans.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.AcnePublished: April 21, 2026

New Skincare Treatment May Help Reduce Acne Symptoms

Researchers developed a new treatment that combines two ingredients to fight acne. They tested this treatment in lab experiments and found it may help reduce inflammation and kill bacteria that cause acne. This treatment uses tiny needles that dissolve in the skin to deliver the ingredients.

Why it matters: This study may help us better understand how to treat acne and reduce its symptoms, but more research is needed to confirm its effectiveness.

This study was conducted in a lab using animal models, so its results may not translate directly to human skin. More research is needed to confirm its effectiveness and safety in humans.

PubMed
Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Systematic ReviewSummary and analysis of existing published studies.Fine LinesPublished: April 20, 2026

Understanding Skin Aging: A New Framework for Anti-aging Strategies

Researchers studied the skin's extracellular microenvironment and found that it consists of three interconnected domains: hydration, nutritional, and signaling. They identified age-related changes in each domain, such as decreased skin water retention and impaired nutrient transport. A small study suggests that targeting these domains may help improve skin appearance.

Why it matters: This research may help us better understand skin aging and develop more effective anti-aging strategies.

This review is based on existing research and does not present new experimental data. The authors discuss various anti-aging strategies, but their effectiveness has not been directly tested in this study.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.Published: April 12, 2026

Researchers developed a new treatment for biofilm infections

A new treatment was studied for its ability to target and kill bacteria that form biofilms, which can be resistant to antibiotics. This treatment uses a combination of heat and light to kill bacteria. In lab experiments, it was found to be effective against mixed-species biofilm infections. Further research is needed to confirm its effectiveness in real-world settings.

Why it matters: This research may help improve our understanding of how to treat bacterial infections that are resistant to antibiotics.

This study was conducted in a lab setting using animal models, and its effectiveness in humans is unknown. Further research is needed to confirm its safety and efficacy in real-world settings.

PubMed