Broad-spectrum light used for pigmentation, redness, and photoaging. Primarily in-clinic procedure.
◆Moderate evidence
The Idea
Intense Pulsed Light (IPL) is a broad-spectrum light-based treatment used for pigmentation, redness, and photoaging. It is primarily administered in-clinic by trained professionals. The proposed mechanism of action involves selective photothermolysis, where the IPL device emits high-intensity pulses of light that target and damage specific skin structures, leading to subsequent removal or reduction of unwanted skin features.
What the Evidence Shows
Research suggests that IPL is effective in reducing pigmentation and photoaging, with studies indicating improvements in skin texture and appearance. A systematic review of 15 clinical trials found that IPL significantly reduced facial pigmentation and improved skin texture. However, evidence is limited regarding the optimal treatment parameters and long-term efficacy. Additionally, the quality of evidence varies across studies, with some reporting high dropout rates and inconsistent outcome measures.
Verdict
The current state of clinical use suggests that IPL is a viable treatment option for pigmentation and photoaging, but its effectiveness can vary depending on individual skin types and treatment parameters. While some studies indicate positive outcomes, the evidence base is limited, and more research is needed to fully understand its efficacy and safety.
Understanding evidence levels▼
In VitroCell or tissue culture experiments — no human or animal data.
Ex VivoSkin model or tissue experiments — not in living humans.
Animal StudyResults in animals only — may or may not translate to humans.
Small Human StudySmall or uncontrolled human study — preliminary results.
Controlled TrialControlled human study (often randomized) — stronger evidence.
Systematic ReviewSummary and analysis of existing published studies.
Meta-AnalysisStatistical pooling of results from multiple studies.
GuidelineProfessional guidance or consensus statement from a dermatology society.
◆ Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Systematic ReviewSummary and analysis of existing published studies.Redness / Facial RednessPublished: July 23, 2026
Lasers and Light Sources May Help Treat Telangiectasias in Certain Skin Conditions
Researchers studied the effectiveness of lasers and light sources in treating telangiectasias associated with systemic sclerosis and lupus erythematosus. They found that pulsed dye laser and intense pulsed light treatments resulted in improvement in telangiectasias in most studies. However, more treatment sessions may be required compared to sporadic telangiectasias.
Why it matters: This research may help guide physicians in managing telangiectasias associated with systemic sclerosis and lupus erythematosus.
The review included 10 studies, but only investigated the use of pulsed dye laser and intense pulsed light. No studies reported exacerbation of the underlying conditions, but more treatment sessions may be required compared to sporadic telangiectasias.
◆ Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Controlled TrialControlled human study, often randomized. Stronger evidence.AcnePublished: July 10, 2026
Lasers May Help Reduce Inflammatory Acne Symptoms
Researchers studied the effectiveness of three laser treatments (PDL, IPL, and Q-Switched Nd: YAG) for moderate to severe inflammatory acne. A small study found that all three treatments reduced acne symptoms, but there was no significant difference between them. Participants reported improved quality of life, but the study had limitations.
Why it matters: This study may help skincare professionals understand the potential benefits and limitations of laser treatments for inflammatory acne.
This study had a small sample size of 36 patients and was a pilot study, so more research is needed to confirm these findings. The study only lasted for three treatment sessions, and the long-term effects of these treatments are not known.
Small Human StudySmall or uncontrolled human study. Results are preliminary.HyperpigmentationPublished: June 26, 2026
New Skincare Treatment May Help Erythromelanosis Follicularis of Faciei and Colli
Researchers studied a new treatment for erythromelanosis follicularis of faciei and colli, a skin condition causing hyperpigmentation and redness. They used a device called Advanced Optimal Pulse Technology to target the condition in 14 patients. The results showed that the treatment reduced redness and melanin levels on the treated side compared to the untreated side. However, more research is needed to confirm these findings.
Why it matters: Understanding this treatment may help people with erythromelanosis follicularis of faciei and colli find more effective options for managing their condition.
The study had a small sample size and lacked long-term follow-up to assess recurrence rates. Additionally, the study was not prospectively registered as a clinical trial.
◆ Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Controlled TrialControlled human study, often randomized. Stronger evidence.Redness / Facial RednessPublished: June 6, 2026
Intense Pulsed Light vs. Diode Laser for Hair Removal: A Study
Researchers studied the effectiveness and safety of intense pulsed light (IPL) and diode laser (DL) for removing hair from the armpits of women with fair to medium skin. Both treatments reduced hair growth, but diode laser showed more favorable results in the long term. However, it also caused more discomfort and temporary side effects.
Why it matters: This study may help people understand the pros and cons of using IPL or DL for hair removal, but more research is needed to confirm these findings.
This study had a small sample size and only followed participants for 7 months after treatment.
Small Human StudySmall or uncontrolled human study. Results are preliminary.HyperpigmentationPublished: June 1, 2026
1,927-nm Laser May Exacerbate Melasma in Some Individuals
Researchers studied the effects of a 1,927-nm laser on melasma, a skin condition causing patches of discoloration. They found that 11% of patients treated with the laser developed worsening melasma or new cases of the condition. The study suggests that the laser may trigger melasma in some people, particularly those with darker skin types and frequent sun exposure.
Why it matters: This study may help skincare professionals understand the potential risks of using this laser treatment for melasma, particularly in individuals with certain skin types or environmental factors.
Retrospective design, lack of objective severity measures, and a small sample size of 116 individuals limit the study's findings.
Ex VivoSkin model or tissue experiments. Not in living humans.HyperpigmentationPublished: May 8, 2026
IPL Therapy's Effects on Melanin-Rich Cells Studied in Lab
Researchers studied how intense pulsed light (IPL) affects cells rich in melanin in a lab setting. They found that higher doses of IPL can increase cellular temperature, induce cell death, and trigger inflammation. This may help us understand how IPL works, but more research is needed to confirm these findings.
Why it matters: This study may help us better understand how IPL therapy works and its potential effects on the skin, which could lead to improved treatments for skin conditions.
This study was conducted in a lab setting using tissue constructs, not human subjects, and involved extreme treatment regimens that may not be representative of typical IPL therapy.
Animal StudyResults in animals only. May or may not translate to humans.WrinklesPublished: May 2, 2026
Intense Pulsed Light May Help Rejuvenate UV-Damaged Skin
Researchers studied how intense pulsed light affects skin damaged by UV radiation. They found that it may help by reducing the activity of certain enzymes involved in skin aging. This was observed in lab experiments and animal studies.
Why it matters: Understanding how intense pulsed light affects skin aging may lead to new treatments for photoaging.
This study was conducted in lab experiments and animal studies, and its findings may not directly apply to human skin. Further research is needed to confirm these results.
◆ Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Controlled TrialControlled human study, often randomized. Stronger evidence.Redness / Facial RednessPublished: May 1, 2026
Hair Reduction Treatments Compared in Pakistani Study
Researchers compared two treatments for excessive hair growth: intense pulsed light and a triple wavelength diode laser. They found that the laser treatment showed better results in the first two months, but the difference was not significant after four months. Both treatments caused some side effects, with the light treatment causing more issues.
Why it matters: Understanding the effectiveness of different hair reduction treatments can help individuals make informed decisions about their skincare options.
This study was conducted in a small group of patients in Pakistan, and the results may not be generalizable to other populations. The study had a relatively short duration of four months, and more long-term studies are needed to confirm the findings.
◆ Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Systematic ReviewSummary and analysis of existing published studies.AcnePublished: April 29, 2026
Photodynamic Therapy in Skincare: Research Review
Photodynamic therapy (PDT) is a treatment that combines a light-sensitive medication, light, and oxygen to target skin issues. Researchers found that PDT may help with certain skin conditions, such as actinic keratosis and acne, but more research is needed to fully understand its effects. PDT was studied for its potential to treat various skin issues, including cancer, inflammation, and infections.
Why it matters: Understanding the potential benefits and limitations of PDT may help individuals with certain skin conditions make informed decisions about their treatment options.
The review included a comprehensive literature search, but the quality and consistency of the evidence varied across different skin conditions. Some studies had small sample sizes or were conducted in lab settings.
◆ Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Controlled TrialControlled human study, often randomized. Stronger evidence.Redness / Facial RednessPublished: February 1, 2026
Cream May Help Skin Recover After IPL Therapy
Researchers studied a cream with soothing ingredients to see if it could help skin recover after intense pulsed light (IPL) therapy. They found that the cream may improve skin hydration and reduce redness and discomfort. However, the study was small and more research is needed to confirm these findings.
Why it matters: Understanding how to help skin recover after IPL therapy could be important for people who undergo this treatment for skin rejuvenation.
A small, randomized, double-blind, split-face study with 30 healthy female subjects, with a short duration of 28 days, and no mention of industry funding.
◆ Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Controlled TrialControlled human study, often randomized. Stronger evidence.Redness / Facial RednessPublished: January 28, 2026
IPL Facial Laser Hair Removal in Transgender Patients: A Four-Year Retrospective Review
Researchers studied the safety and effectiveness of intense pulsed light (IPL) laser hair removal in a group of 115 transgender patients. They found that most patients experienced common side effects like redness and swelling, but no serious complications occurred. The study suggests that personalized laser settings and close monitoring may be important for successful treatment.
Why it matters: This study may help skincare professionals understand how to safely and effectively use IPL laser hair removal for transgender patients.
This study was a retrospective review of existing patient data, which may not be as reliable as a prospective study. The sample size was relatively small, and more research is needed to confirm these findings.
Small Human StudySmall or uncontrolled human study. Results are preliminary.TretinoinRedness / Facial RednessPublished: January 1, 2026
Morbihan Disease May Cause Skin Inflammation Beyond the Face
Researchers studied a man with Morbihan disease, a rare skin condition, and found that it may cause inflammation in areas beyond the face. The patient developed skin problems on his inner thighs, trunk, and upper limbs. Treatment with isotretinoin provided sustained remission, but more research is needed to confirm these findings.
Why it matters: This study may help us better understand the progression of Morbihan disease and its potential impact on the body.
This case report is based on a single patient and requires further investigation to confirm its findings. The study's small sample size and lack of control group limit its conclusions.