Acne

A skin condition characterized by comedones, papules, pustules, and cysts. A medically significant concern requiring careful product selection.

Understanding evidence levels
In VitroCell or tissue culture experiments — no human or animal data.
Ex VivoSkin model or tissue experiments — not in living humans.
Animal StudyResults in animals only — may or may not translate to humans.
Small Human StudySmall or uncontrolled human study — preliminary results.
Controlled TrialControlled human study (often randomized) — stronger evidence.
Systematic ReviewSummary and analysis of existing published studies.
Meta-AnalysisStatistical pooling of results from multiple studies.
GuidelineProfessional guidance or consensus statement from a dermatology society.

Research findings(350)

In VitroCell or tissue culture experiments. No human or animal data.Lactic AcidPublished: April 27, 2026

Postbiotic May Help Support Balanced Skin Microbiome

Researchers studied a postbiotic called PS-B1, made from fermented soy milk, to see how it affects beneficial skin bacteria. They found that a preservative-free version of PS-B1 may help some beneficial bacteria grow in lab experiments. However, more research is needed to confirm these findings.

Why it matters: Understanding how to support a balanced skin microbiome may be important for maintaining healthy skin.

This study was conducted in lab experiments and only looked at the effects of PS-B1 on a small number of skin bacteria strains. Further research is needed to confirm these findings and see if they apply to real-world skin health.

PubMed
Ex VivoSkin model or tissue experiments. Not in living humans.Published: April 23, 2026

Delafloxacin-Loaded Ethosomal Gel May Help Treat Skin Infections

Researchers studied a new type of gel that contains an antibiotic called delafloxacin. They found that this gel may help deliver the antibiotic more effectively to the skin, which could improve its ability to fight bacterial infections. However, more research is needed to confirm these findings.

Why it matters: This study may help us better understand how to treat skin infections, which can be painful and difficult to treat.

This study was conducted in a lab and used animal models, so its findings may not directly apply to humans. Further research is needed to confirm these results.

PubMed
Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Systematic ReviewSummary and analysis of existing published studies.Published: April 22, 2026

Combining lasers and platelet-rich plasma may help improve chronic scars

Researchers studied the combination of ablative fractional carbon dioxide lasers and platelet-rich plasma for treating chronic scars caused by acne, burns, and trauma. They found that this combination may improve scar texture, pigmentation, and depth, and increase patient satisfaction. However, the results varied across different studies.

Why it matters: Understanding how to effectively treat chronic scars can help individuals with these conditions manage their appearance and improve their quality of life.

The studies included in the review had varying laser settings, PRP preparation methods, and outcome measures, which limits direct comparison of the results. Robust multicentre randomised trials are needed to establish parameter-specific guidelines for this therapy.

PubMed
In VitroCell or tissue culture experiments. No human or animal data.RetinolPublished: April 21, 2026

Researchers Develop New Microspheres for Controlled Release of Skincare Ingredients

Scientists created tiny microspheres that can release two skincare ingredients, retinol and salicylic acid, in a controlled way. This may help improve the delivery of these ingredients to the skin. The microspheres were designed to release the ingredients in response to the skin's pH levels.

Why it matters: This research may lead to more effective skincare treatments for conditions like acne and psoriasis.

This study was conducted in a lab setting and has not been tested in humans. The effectiveness of these microspheres in real-world skincare applications is unknown.

PubMed
Small Human StudySmall or uncontrolled human study. Results are preliminary.Published: April 21, 2026

Minimally Invasive Cosmetic Procedures Evaluated for Efficacy and Safety

Researchers studied the effectiveness and safety of three minimally invasive cosmetic procedures: dermabrasion, fat grafting, and fibrous septa release. The procedures were used to address skin texture irregularities, volume loss, and cellulite. A small study found that these procedures may help improve appearance, but more research is needed to confirm these findings.

Why it matters: Understanding the efficacy and safety of these procedures may help individuals make informed decisions about their skincare and cosmetic treatments.

This study had a small sample size of 150 patients and was retrospective, meaning it looked back at existing data. Future prospective studies with larger cohorts and long-term follow-up are recommended to validate these findings.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.Hyaluronic AcidPublished: April 21, 2026

New Skincare Treatment May Help Reduce Acne Symptoms

Researchers developed a new treatment that combines two ingredients to fight acne. They tested this treatment in lab experiments and found it may help reduce inflammation and kill bacteria that cause acne. This treatment uses tiny needles that dissolve in the skin to deliver the ingredients.

Why it matters: This study may help us better understand how to treat acne and reduce its symptoms, but more research is needed to confirm its effectiveness.

This study was conducted in a lab using animal models, so its results may not translate directly to human skin. More research is needed to confirm its effectiveness and safety in humans.

PubMed
Small Human StudySmall or uncontrolled human study. Results are preliminary.Published: April 20, 2026

Community-based dermatology clinic may improve skin care for Aboriginal and Torres Strait Islander peoples

A small study in Australia looked at a new community-based dermatology clinic for Aboriginal and Torres Strait Islander peoples. Researchers found that patients valued the clinic's accessibility and culturally safe environment. The clinic may help improve skin care for this group, but more research is needed.

Why it matters: This study may help improve understanding of how to provide better skin care for Aboriginal and Torres Strait Islander peoples, who experience a disproportionate burden of skin conditions.

This study had a small sample size and was conducted in a single urban location. Further research is needed to confirm these findings and determine their generalizability to other populations.

PubMed
Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Systematic ReviewSummary and analysis of existing published studies.Published: April 14, 2026

Phototherapy May Help Manage Acne Symptoms

Researchers studied phototherapy for acne vulgaris, a chronic inflammatory skin disease. They found that different light-based treatments can target acne through three main pathways: reducing sebum production, controlling inflammation, and improving scar appearance. The effectiveness of these treatments varies depending on the individual's acne type and severity.

Why it matters: Understanding phototherapy's potential benefits and limitations may help individuals with acne make informed decisions about their treatment options.

This review is based on studies published between 2005 and 2025, and the findings may not be applicable to all individuals with acne. The effectiveness of phototherapy can vary depending on the specific treatment and individual characteristics.

PubMed
Small Human StudySmall or uncontrolled human study. Results are preliminary.Published: April 11, 2026

Dual Wave Radiofrequency Microneedling May Help Acne Scarring in Darker Skin Types

A small study looked at a new treatment for acne scarring and dark spots in people with darker skin. Researchers found that a dual-wave radiofrequency microneedling device improved acne scarring and dark spots in most participants. However, the study had limitations and more research is needed to confirm these findings.

Why it matters: This study may help expand treatment options for acne scarring and dark spots in people with darker skin types.

This study had a small sample size, was not blinded, and lacked a control group. More research is needed to confirm these findings and compare this treatment to others.

PubMed
Animal StudyResults in animals only. May or may not translate to humans.Published: April 10, 2026

α-terpinolene may help reduce acne inflammation and hyperkeratosis

Researchers studied the effects of α-terpinolene, a compound found in pine needles, on acne-causing bacteria and skin inflammation. In lab experiments and mouse models, α-terpinolene showed promise in reducing inflammation and hyperkeratosis associated with acne. However, more research is needed to confirm these findings.

Why it matters: Understanding how α-terpinolene affects acne could lead to new treatments or ingredients for skincare products.

This study was conducted in lab experiments and mouse models, and more research is needed to confirm its findings in humans. The study's results may not translate directly to human skin or acne conditions.

PubMed
Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Controlled TrialControlled human study, often randomized. Stronger evidence.Published: April 10, 2026

Truncal Acne May Have a Greater Impact on Quality of Life

A study of 2038 patients with acne found that those with both facial and truncal acne experienced greater symptoms and impaired health-related quality of life compared to those with facial acne alone. Researchers found that patients with combined facial and truncal acne had higher scores on a scale measuring quality of life and anxiety and depression. The study suggests that truncal acne may be more common than previously thought.

Why it matters: Understanding the impact of truncal acne on quality of life may help dermatologists provide better care for patients with this condition.

This study was a retrospective analysis of a secondary-care cohort, and the results may not be generalizable to other populations.

PubMed
Notable findingA finding from a controlled trial, systematic review, or meta-analysis with noteworthy results.Systematic ReviewSummary and analysis of existing published studies.Published: April 7, 2026

Topical Vitamins May Help with Skin Conditions and Aging

Researchers studied the uses and limitations of topical vitamins in dermatology. They found that these vitamins have anti-inflammatory, antioxidant, and moisturizing properties, which may help with skin conditions like psoriasis and acne. However, their effectiveness and stability can be limited by formulation challenges and side effects.

Why it matters: Understanding the potential benefits and limitations of topical vitamins may help individuals make informed decisions about their skincare routines.

The study's findings are based on a review of existing research, and more studies are needed to confirm the effectiveness of topical vitamins for various skin conditions.

PubMed